Gastrulation: Nodal signaling controls ordered collective cell migration

Hernan Morales-Navarrete; Patrick Müller

doi:10.1016/j.cub.2022.11.018

Gastrulation: Nodal signaling controls ordered collective cell migration

Curr Biol. 2022 Dec 19;32(24):R1354-R1356. doi: 10.1016/j.cub.2022.11.018.

Authors

Hernan Morales-Navarrete¹, Patrick Müller²

Affiliations

¹ University of Konstanz, Centre for the Advanced Study of Collective Behaviour, Universitätsstraße 10, 78464 Konstanz, Germany.
² University of Konstanz, Centre for the Advanced Study of Collective Behaviour, Universitätsstraße 10, 78464 Konstanz, Germany. Electronic address: patrick.mueller@uni-konstanz.de.

PMID: 36538889
DOI: 10.1016/j.cub.2022.11.018

Abstract

By combining classical embryological experiments, advanced imaging, and active-particle simulations, a new study reveals how the coupling of signaling and active mechanical forces triggers the collective ordered internalization of mesendoderm cells during gastrulation in zebrafish embryos.

MeSH terms

Animals
Cell Movement
Gastrulation*
Signal Transduction
Zebrafish Proteins
Zebrafish*

Substances

Zebrafish Proteins