Intracranial Corkscrew Angiopathy

Neurol Clin Pract. 2022 Dec;12(6):e228-e231. doi: 10.1212/CPJ.0000000000200088.


Objectives: The objective of this case report was to describe a rare presentation of corkscrew cerebral angiopathy presenting as subarachnoid hemorrhage (SAH).

Methods: We present a young woman who presented with a thunderclap headache, found to have a nonaneurysmal SAH.

Results: Cerebral angiogram revealed corkscrew angiopathy in medium-sized vessels and multiple micro-occlusions with collateralization. No intracranial aneurysm was detected. Extensive workup for vasculitis and genetic causes for vasculopathy was unrevealing. The patient had no neurologic deficits, and her symptoms resolved.

Discussion: This is an extremely rare presentation of subarachnoid hemorrhage due to corkscrew angiopathy.