The programming and execution of movement sequences in Parkinson's disease

Int J Neurosci. 1987 Sep;36(1-2):55-65. doi: 10.3109/00207458709002139.


Parkinsonian and neurologically normal subjects performed a finger-tapping task in which different sequence lengths had to be executed as rapidly as possible. For each response sequence, reaction time (RT), inter-tap-intervals (ITIs) and error patterns were recorded. It was found that the RT-sequence length relationship as well as the group ITI data were different for the two groups, indicative of impaired programming in the Parkinsonian subjects. This conclusion was supported by a relative dissociation of the first and subsequent taps and by a pattern of progressively increasing errors with longer tap sequences in the Parkinsonians.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aged
  • Female
  • Humans
  • Male
  • Middle Aged
  • Motor Activity / physiology*
  • Parkinson Disease / physiopathology*
  • Reaction Time / physiology