Vulvar carcinoma and its recurrences - principles of surgical treatment

Ceska Gynekol. 2022;87(6):401-407. doi: 10.48095/cccg2022401.


Objective: A comprehensive overview of the surgical treatment of vulvar cancer, including recurrent forms.

Methodology: A review work providing a basic overview of the pathogenesis, dia-gnosis and surgical treatment of vulvar cancer with a focus on the possibilities of treatment of its recurrences. It includes an illustrative case report presenting a patient with invasive squamous cell carcinoma of the vulva with iterative local recurrences and subsequent development of tumor triplicity and distant metastatic involvement.

Conclusion: Surgical treatment remains the main modality of vulvar cancer therapy, even in the case of locally advanced or recurrent findings. In these cases, multidisciplinary cooperation of operational fields is necessary. The discipline of treated patients with participation in regular dispensary care plays an important role in the early detection of recurrences. (Chemo) radiotherapy remains a possible alternative to the surgical solution; in clinical practice, radiotherapy has an irreplaceable place in adjuvant therapy. Regional and distant recurrences are characterized by a poor prognosis.

Keywords: Chemoradiotherapy; concurrent chemoradiotherapy; distant recurrence; groin (inguinal) recurrence; local recurrence; operative treatment; surgery; vulvar cancer.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Carcinoma, Squamous Cell* / pathology
  • Carcinoma, Squamous Cell* / surgery
  • Female
  • Humans
  • Neoplasm Recurrence, Local / pathology
  • Neoplasm Staging
  • Recurrence
  • Retrospective Studies
  • Vulva / pathology
  • Vulvar Neoplasms* / pathology
  • Vulvar Neoplasms* / surgery