Demonstration that glycoprotein G is the attachment protein of respiratory syncytial virus

J Gen Virol. 1987 Sep;68 ( Pt 9):2521-4. doi: 10.1099/0022-1317-68-9-2521.

Abstract

Two monospecific rabbit antisera to the G glycoprotein, one induced with purified G and the second with a recombinant vaccinia virus containing the gene for G, inhibit the attachment of purified [35S]methionine-labelled Long strain of respiratory syncytial virus to monolayers of HeLa cells. Attachment was not inhibited by monospecific rabbit antisera to glycoprotein F induced with either purified F or with a recombinant vaccinia virus containing the gene for F.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Monoclonal
  • Enzyme-Linked Immunosorbent Assay
  • HeLa Cells / microbiology
  • Humans
  • Immune Sera
  • Kinetics
  • Respiratory Syncytial Viruses / metabolism*
  • Viral Envelope Proteins / immunology
  • Viral Envelope Proteins / metabolism*

Substances

  • Antibodies, Monoclonal
  • Immune Sera
  • Viral Envelope Proteins