Insect antifeedant activity and hot taste for humans of selected natural and synthetic 1,4-dialdehydes

J Nat Prod. Mar-Apr 1987;50(2):146-51. doi: 10.1021/np50050a002.

Abstract

The antifeedant activity towards larvae of Leptinotarsa decemlineata and Spodoptera littoralis and the hot taste for the human tongue have been determined for natural and synthetic 1,4-dialdehydes. Among the bicyclic dialdehydes the biological activity has been found to be dependent on the distance between the two aldehyde groups; tricyclic and pentacyclic dialdehydes are inactive in both tests. A short synthetic route to (-)- and (+)-polygodial is reported.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehydes / chemical synthesis
  • Aldehydes / pharmacology*
  • Animals
  • Chemical Phenomena
  • Chemistry
  • Feeding Behavior / drug effects*
  • Humans
  • Insecta / physiology*
  • Structure-Activity Relationship
  • Taste / drug effects*

Substances

  • Aldehydes