Radiological and pathological characteristics of synovial hemangioma of the knee

Exp Ther Med. 2022 Nov 23;25(1):23. doi: 10.3892/etm.2022.11722. eCollection 2023 Jan.

Abstract

Synovial hemangioma, a rare benign tumor that occurs most frequently in the knee in children and young adults, has four histological subtypes: Venous, arteriovenous, cavernous and capillary hemangiomas. Since the clinical presentation and radiological findings of synovial hemangioma are non-specific, there is frequently a long period between the onset and the diagnosis. The cases of nine patients, pathologically diagnosed with synovial hemangioma and surgically treated, were retrospectively analyzed. All nine patients had persistent knee pain. In addition, three patients also had a swollen knee with intra-articular hemorrhage. Plain radiography revealed intra-articular phleboliths in two patients. In seven patients, T1-weighted magnetic resonance imaging showed low signal intensity with small signal voids. On T2-weighted imaging, all patients showed high signal intensity containing small signal voids. All patients underwent surgical excision; there was no postoperative recurrence after the final operation, and the knee pain had disappeared at the final follow-up. From the pathological findings, the diagnoses were venous hemangioma, cavernous hemangioma and capillary hemangioma (three patients each).

Keywords: apparent diffusion coefficient; diffuse-type tenosynovial giant cell tumor; intra-articular tumor; knee; magnetic resonance imaging; synovial hemangioma.

Grants and funding

Funding: This work was partially supported by JSPS KAKENHI (grant no. JP21K09304).