Association Between Opioid Use and Outpatient Visits for Dysphagia: An Analysis of the National Ambulatory Medical Care Survey in 2008-2018

Clin Transl Gastroenterol. 2023 Mar 1;14(3):e00552. doi: 10.14309/ctg.0000000000000552.

Abstract

Introduction: Opioid-induced esophageal dysfunction has been described with characteristic manometric patterns, but the population burden of dysphagia attributable to opioid use remains unclear.

Methods: The National Ambulatory Medical Care Survey from 2008 to 2018 was used to assess the relationship between opioid use and outpatient visits for dysphagia.

Results: After controlling for potential confounders, there were no significant difference in ambulatory visits for dysphagia between opioid users and nonusers (adjusted odds ratio = 0.98, confidence interval: 0.59-1.65).

Discussion: No correlation between opioid use and ambulatory visits for dysphagia was found in a nationwide sample. Opioid-related manometric changes may be clinically relevant only in a small proportion of patients.

MeSH terms

  • Analgesics, Opioid* / adverse effects
  • Deglutition Disorders* / diagnosis
  • Deglutition Disorders* / epidemiology
  • Health Care Surveys
  • Humans
  • Odds Ratio
  • Outpatients

Substances

  • Analgesics, Opioid