Cu2+ assisted carnation-like fluorescent metal-organic framework for triple-mode detection of glyphosate in food samples

Jianping Guan; Qing He; Qi Liu; Xiaoqing Chen

doi:10.1016/j.foodchem.2022.135237

Cu²⁺ assisted carnation-like fluorescent metal-organic framework for triple-mode detection of glyphosate in food samples

Food Chem. 2023 May 15:408:135237. doi: 10.1016/j.foodchem.2022.135237. Epub 2022 Dec 16.

Authors

Jianping Guan¹, Qing He¹, Qi Liu², Xiaoqing Chen³

Affiliations

¹ College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, Hunan, China.
² College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, Hunan, China. Electronic address: iliuqi@csu.edu.cn.
³ College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, Hunan, China; Key Laboratory of Hunan Province for Water Environment and Agriculture Product Safety, Central South University, Changsha 410083, Hunan, China. Electronic address: xqchen@csu.edu.cn.

PMID: 36563622
DOI: 10.1016/j.foodchem.2022.135237

Abstract

Herein, by employing a novel synthesized ligand H₂L, a flower-like luminescent metal-organic framework IRMOF-3-L was constructed for developing a triple-mode sensor for glyphosate (Glyp) detection. The ligand H₂L was designed to contain three functional parts, which endowed the resulted IRMOF-3-L with peroxidase-like activity and unique fluorescence property, as well as specific combining capacity for Cu²⁺ to quench its fluorescence. The quenched fluorescence of IRMOF-3-L/Cu²⁺ could be recovered by Glyp to realize fluorescence detection of Glyp. Besides, the peroxidase activity of IRMOF-3-L/Cu²⁺ could also be inhibited by Glyp, and result in the decrease of catalysate oxTMB, concurrently reducing the changes of colorimetric and SERS signal. Therefore, the fluorescent/colorimetric/SERS triple-mode based detection of Glyp was favorably realized, and the detection limits were calculated as low as 0.738, 2.26 and 0.186 nM, respectively. Furthermore, a portable test strips-smartphone sensing platform was constructed for point of care testing of Glyp in food samples.

Keywords: Food analysis; Glyphosate; Metal-organic framework; Multiple-mode detection; POCT.

MeSH terms

Coloring Agents
Dianthus*
Fluorescent Dyes
Ligands
Metal-Organic Frameworks*
Peroxidases

Substances

Metal-Organic Frameworks
zinc 2-amino-1,4-benzenedicarboxylic
glyphosate
Ligands
Coloring Agents
Peroxidases
Fluorescent Dyes