Infant in extremis: respiratory failure secondary to lower airway infantile hemangioma

BMC Pediatr. 2022 Dec 30;22(1):744. doi: 10.1186/s12887-022-03821-1.

Abstract

Background: Infantile hemangiomas (IHs) are vascular tumors that commonly affect infants and usually regress spontaneously or can be easily treated as an outpatient with topical beta-blockers. However, IHs that present in the airway may cause life-threatening symptoms due to airway obstruction or risk of bleeding. Here we present the first documented case of an infant with rapid deterioration and acute respiratory failure secondary to a lower airway hemangioma.

Case presentation: This 3-month-old male initially presented in respiratory distress with symptoms consistent with a viral respiratory infection, however showed no clinical improvement with standard therapies. An urgent CT scan revealed a mass occluding the right mainstem bronchus. Upon transfer to a tertiary care facility, he developed acute respiratory failure requiring emergent intubation and single lung ventilation. The availability of multiple subspecialists allowed for stabilization of a critically ill child, expedited diagnosis, and ultimately initiation of life-saving treatment with beta blockers. After 17 total hospital days, he was extubated successfully and discharged home in good condition.

Conclusions: While IH is a rare cause of infantile respiratory distress, we present multiple pearls for the general pediatrician for management of IHs of the airway.

Keywords: Bronchial compression; Case report; Dermatology; Otolaryngology; Vascular malformation.

Publication types

  • Case Reports

MeSH terms

  • Adrenergic beta-Antagonists / therapeutic use
  • Airway Obstruction* / etiology
  • Airway Obstruction* / therapy
  • Child
  • Hemangioma* / complications
  • Hemangioma, Capillary* / complications
  • Humans
  • Infant
  • Male
  • Respiratory Distress Syndrome* / complications
  • Respiratory Distress Syndrome* / drug therapy

Substances

  • Adrenergic beta-Antagonists