Visual acuity loss in patients with Stargardt's macular dystrophy

Ophthalmology. 1987 Jul;94(7):809-14. doi: 10.1016/s0161-6420(87)33533-x.


Ninety-five patients with Stargardt's macular dystrophy were appraised for visual loss with age by both life-table analyses and cross-sectional procedures. The probability of maintaining a visual acuity of 20/40 or better in at least one eye was 52% by age 19, 32% by age 29, and 22% by age 39. In the population studied, once a patient's visual acuity dropped below 20/40, it tended to decrease rapidly and stabilize at 20/200. Fluorescein angiograms obtained on 64 of the 95 patients showed a "dark choroid" in 55 (85.9%). This finding, therefore was present in the majority of the patients, although its absence does not rule out Stargardt's macular dystrophy.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Actuarial Analysis
  • Adolescent
  • Adult
  • Aged
  • Child
  • Child, Preschool
  • Female
  • Fluorescein Angiography
  • Humans
  • Macula Lutea*
  • Male
  • Middle Aged
  • Retinal Diseases / pathology
  • Retinal Diseases / physiopathology*
  • Visual Acuity*