Acupuncture in the Treatment of Panitumumab Skin Toxicity: A Case Report

Complement Med Res. 2023;30(1):78-83. doi: 10.1159/000527853. Epub 2023 Jan 3.

Abstract

Background: Inflammatory skin rash resulting from treatment with epidermal growth factor receptor inhibitors may cause physical and mental disabling to patients treated for their oncologic condition and may, in some cases, lead to the cessation of biological treatment.

Case report: In this case report, acupuncture treatment was provided to a patient with metastatic colorectal carcinoma who developed skin toxicity from panitumumab including rash, itching, and skin inflammation. Itching, infection, and inflammation symptoms improved significantly following acupuncture, subsequently relapsed following treatment cessation, and improved once again following reintroduction of acupuncture.

Conclusion: Acupuncture may be effective in alleviating panitumumab-related skin inflammatory symptoms.

Keywords: Acupuncture; Case report; Colorectal adenocarcinoma; Epidermal growth factor receptor inhibitors; Skin toxicity.

Publication types

  • Case Reports

MeSH terms

  • Acupuncture Therapy*
  • Antibodies, Monoclonal / adverse effects
  • Humans
  • Inflammation / chemically induced
  • Inflammation / complications
  • Panitumumab / adverse effects
  • Pruritus
  • Skin Diseases*

Substances

  • Panitumumab
  • Antibodies, Monoclonal