Statins may increase diabetes, but benefit still outweighs risk

Cleve Clin J Med. 2023 Jan 3;90(1):53-62. doi: 10.3949/ccjm.90a.22069.


Data have been accumulating on the risk of developing type 2 diabetes in patients receiving statins and on the potential adverse effects of these drugs on glycemic control in patients who already have type 2 diabetes. This article reviews data linking statin use and new-onset diabetes mellitus, the effects of statins on glycemic control in type 2 diabetes, the benefit-risk considerations of statin use and type 2 diabetes, and how these factors affect patient management.

Publication types

  • Review

MeSH terms

  • Cardiovascular Diseases* / chemically induced
  • Diabetes Mellitus, Type 2* / drug therapy
  • Drug-Related Side Effects and Adverse Reactions*
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors* / adverse effects
  • Risk Assessment
  • Risk Factors


  • Hydroxymethylglutaryl-CoA Reductase Inhibitors