Herbal topical anesthetics in dentistry: an exploratory review

J Dent Anesth Pain Med. 2022 Dec;22(6):419-426. doi: 10.17245/jdapm.2022.22.6.419. Epub 2022 Nov 24.


Topical anesthetics are routinely used in dental practice for various purposes. They are usually available at higher dosages and have serious potential adverse reactions, such as seizures, anaphylaxis, and acquired methemoglobinemia. To date, the scope of application of herbal plants and their extracts, which have medicinal properties, has been elaborated in the field of dentistry. The growing interest in herbal medication can be attributed to the increased safety profile of herbal agents, in contrast to synthetic preparations that have a higher risk of systemic complications. Herbal preparations can induce topical anesthesia with minimal side effects. Recently, many studies have reported the use of topical herbal preparations. The current review aimed to evaluate data from various articles comparing the capacity of herbal topical anesthetic formulations and conventional synthetic anesthetics in reducing pain perception when used as local anesthesia before dental procedures.

Keywords: Dental Anesthesia; Herbal; Topical Administrations.

Publication types

  • Review