Cavernous mediastinal hemangioma presenting with persistent cough: a rare case report and review of literature

J Cardiothorac Surg. 2023 Jan 5;18(1):3. doi: 10.1186/s13019-023-02130-7.


Background: Cavernous hemangioma is a rare benign tumor which can sometimes mimic the clinical presentation and radiological findings of malignant tumors. Here we present a rare presentation of cavernous hemangioma in the mediastinum (CHM), along with a literature review among the main databases.

Case presentation: We present a 48-year-old male who had suffered from persistent cough as the sole symptom of an anterior CHM. Computed tomography scan demonstrated a 12.5 × 10.8 cm mass in the anterior mediastinum. The mass was surgically resected, and histopathological evaluation established the diagnosis of CHM. The patient was discharged in good condition, in which during his four-month follow-up period, no recurrence of the tumor has been observed.

Conclusion: Although cavernous hemangioma rarely present in the mediastinum, it should be considered in the differential diagnosis of mediastinal tumors. However, our review of literature demonstrated a female dominance and average age of 40 years, with a 52% mortality rate based on previous reports.

Keywords: Case report; Cavernous hemangiomas; Hemangioma; Mediastinal neoplasms; Mediastinum.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Adult
  • Cough / etiology
  • Female
  • Hemangioma*
  • Hemangioma, Cavernous* / diagnosis
  • Hemangioma, Cavernous* / diagnostic imaging
  • Humans
  • Male
  • Mediastinal Neoplasms* / complications
  • Mediastinal Neoplasms* / diagnosis
  • Mediastinal Neoplasms* / surgery
  • Mediastinum / diagnostic imaging
  • Mediastinum / pathology
  • Middle Aged