Intradetrusor OnabotuliniumtoxinA injection for refractory bladder spasms before vesicovaginal fistula repair

Urol Case Rep. 2022 Dec 25:46:102307. doi: 10.1016/j.eucr.2022.102307. eCollection 2023 Jan.


This is a report of a women who failed 2 surgical repairs of vesicovaginal fistula secondary to refractory bladder spasms. After each surgical procedure - the hysterectomy and subsequent fistula repairs - the patient reported severe bladder spasms refractory to medical management. Our treatment was intradetrusor onabotuliniumtoxinA injections 4 weeks prior to a planned surgical fistula repair. The patient had successful vaginal approach fistula repair and has not required any subsequent overactive bladder (OAB) treatment.

Keywords: B&O, belladonna and opioid; Botox, onabotuliniumtoxinA; Detrusor spasm; OAB, overactive bladder; Overactive bladder; UTI, urinary tract infection; VVF, vesico-vaginal fistula; Vesicovaginal fistula; onabotuliniumtoxinA.

Publication types

  • Case Reports