A laboratory procedure for the induction of flashbacks

Am J Psychiatry. 1987 Oct;144(10):1317-9. doi: 10.1176/ajp.144.10.1317.

Abstract

The authors administered infusions of lactate intravenously to seven patients with a DSM-III diagnosis of posttraumatic stress disorder, six of whom also met DSM-III criteria for panic disorder. The lactate infusions resulted in flashbacks in all seven patients and panic attacks in six patients. The authors conclude that with further development intravenous lactate infusion may be used to study flashbacks and other dissociative phenomena and to determine the relationship between flashbacks and panic anxiety.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Anxiety Disorders / chemically induced*
  • Anxiety Disorders / complications
  • Anxiety Disorders / psychology
  • Dissociative Disorders / chemically induced*
  • Fear*
  • Glucose / administration & dosage
  • Humans
  • Infusions, Intravenous
  • Isoproterenol / administration & dosage
  • Lactates / administration & dosage*
  • Lactic Acid
  • Panic*
  • Research Design
  • Stress Disorders, Post-Traumatic / complications
  • Stress Disorders, Post-Traumatic / psychology*

Substances

  • Lactates
  • Lactic Acid
  • Glucose
  • Isoproterenol