The potential role of the three-dimensional-bioprinting model in screening and developing drugs

World J Gastroenterol. 2022 Dec 21;28(47):6788-6790. doi: 10.3748/wjg.v28.i47.6788.


Recently, we have read with great interest the original article used different spatial configuration models of colorectal cancer (CRC) for validating the anti-tumor efficacy with Diiminoquinone. We feel obliged to provide new insight into the drug screening models by integrating and analyzing the original method and result. These comments may provide comprehensive insights into three-dimensional drug screening models and the difference between pathologic subtypes in CRC.

Keywords: Colorectal cancer; Drug screening models; Mucinous adenocarcinoma; three-dimensional-bioprinting.

MeSH terms

  • Bioprinting*
  • Humans
  • Neoplasms*