Tracking antimicrobial stewardship activities beyond days of therapy (DOT): Comparison of days of antibiotic spectrum coverage (DASC) and DOT at a single center

Infect Control Hosp Epidemiol. 2023 Jun;44(6):934-937. doi: 10.1017/ice.2022.312. Epub 2023 Jan 10.


Even though antimicrobial days of therapy did not significantly decrease during a period of robust stewardship activities at our center, we detected a significant downward trend in antimicrobial spectrum, as measured by days of antibiotic spectrum coverage (DASC). The DASC metric may help more broadly monitor the effect of stewardship activities.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Anti-Infective Agents*
  • Antimicrobial Stewardship*
  • Humans


  • Anti-Bacterial Agents
  • Anti-Infective Agents