Meta-organismal metabolism in cardiovascular disease

Min Soo Kim; Jordan E Bisanz

doi:10.1016/j.chom.2022.12.007

Meta-organismal metabolism in cardiovascular disease

Cell Host Microbe. 2023 Jan 11;31(1):1-2. doi: 10.1016/j.chom.2022.12.007.

Authors

Min Soo Kim¹, Jordan E Bisanz²

Affiliations

¹ Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA 16802, USA.
² Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA 16802, USA; The Penn State Microbiome Center, Huck Institutes of the Life Sciences, University Park, PA 16802, USA. Electronic address: jordan.bisanz@psu.edu.

PMID: 36634617
DOI: 10.1016/j.chom.2022.12.007

Abstract

Host and microbe cooperate to generate bioactive metabolites with significant scientific and clinical importance. In this issue of Cell Host & Microbe, Zhu, Dwidar et al. identify parallel microbial pathways that transform dietary amino acids into the precursors of deleterious host-derived metabolites and confirm their correlation to adverse cardiovascular health.

Publication types

Comment

MeSH terms

Cardiovascular Diseases*
Diet
Humans

Grants and funding

R00 AI147165/AI/NIAID NIH HHS/United States