Limosilactobacillus walteri sp. nov., a novel probiotic antimicrobial lipopeptide-producing bacterium

FEMS Microbiol Lett. 2023 Jan 17:370:fnad004. doi: 10.1093/femsle/fnad004.

Abstract

A Gram-positive facultative anaerobe, nonspore forming, and nonmotile bacterial strain M31 was isolated from faecal contaminated soil. The strain is previously reported to produce a novel antimicrobial lipopeptide and displayed probiotic properties. The strain M31 is catalase negative and fermented d-galactose, d-glucose, esculin, d-maltose, d-lactose, d-melibiose, d-raffinose, d-saccharose (weak reaction), d-xylose (weak reaction), d-ribose (weak reaction), and l-arabinose (weak reaction). The majority of fatty acids were C16:0 (53.9%), C18:0 (26.9%), and C19:0 cyclo ω8c (19.1%). The genome is 2 234 040 bp long with 38.81% guanine-cytosine (GC) content. The pairwise ortho average nucleotide identity and digital DNA-DNA hybridization values of strain M31 with its closest relative species from Limosilactobacillus reuteri clade and Lm. rudii is below the recommended cut-off of 95% and 70%, respectively. Herein, we propose Lm. walteri sp. nov. as a novel species of the genus Limosilactobacillus with M31 = MTCC 12838 = JCM 32759 = KCTC 25569.

Keywords: Limosilactobacillus walteri sp. nov; bacteria; genome; phylogeny; probiotic; taxonogenomics.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Infective Agents*
  • Bacteria / genetics
  • Bacterial Typing Techniques
  • DNA, Bacterial / genetics
  • Fatty Acids* / analysis
  • Nucleic Acid Hybridization
  • Phospholipids / chemistry
  • Phylogeny
  • RNA, Ribosomal, 16S / genetics
  • Sequence Analysis, DNA

Substances

  • DNA, Bacterial
  • Fatty Acids
  • Anti-Infective Agents
  • RNA, Ribosomal, 16S
  • Phospholipids