Clinical Study on the Risk Factors for the Recurrence of Papillary Thyroid Carcinoma

ORL J Otorhinolaryngol Relat Spec. 2023;85(2):104-108. doi: 10.1159/000528540. Epub 2023 Jan 17.


Introduction: Papillary thyroid carcinoma is the most common endocrine malignancy and the most common type of thyroid cancer, accounting for approximately 85% of all thyroid cancer cases. It usually has a favorable course, with the 10-year survival rate exceeding 90%. However, the literature reports a recurrence rate of 7-23% after initial surgical treatment. It is important to consider medical treatment policies for this recurrence.

Methods: In this study, we examined the risk factors for the recurrence of papillary thyroid carcinoma. We treated 274 patients with thyroid papillary carcinoma at our hospital between 2009 and 2018.

Results: Recurrence occurred in 20 cases (7.3%). Lympho-vascular invasion and lateral cervical lymph node metastasis made significant independent contributions.

Conclusion: The selection of the surgical mode should be based on the recurrence and after comprehensive consideration of the clinical features.

Keywords: Lateral cervical lymph node metastasis; Lympho-vascular invasion; Papillary thyroid carcinoma; Risk factor of recurrence.

MeSH terms

  • Carcinoma, Papillary* / secondary
  • Carcinoma, Papillary* / surgery
  • Humans
  • Lymph Nodes / pathology
  • Lymphatic Metastasis / pathology
  • Neck Dissection
  • Neoplasm Recurrence, Local / pathology
  • Retrospective Studies
  • Risk Factors
  • Thyroid Cancer, Papillary / surgery
  • Thyroid Neoplasms* / pathology
  • Thyroid Neoplasms* / surgery
  • Thyroidectomy