Bilateral primary breast Burkitt's lymphoma in pregnancy

BMJ Case Rep. 2023 Jan 17;16(1):e251896. doi: 10.1136/bcr-2022-251896.

Abstract

Pregnancy-associated cancer is defined as malignancy diagnosed during gestation or up to 1 year post partum. Treatment of cancer during pregnancy is complicated by the risk of harm to the fetus and limitations in safety data. Postpartum patients receiving chemotherapy, tyrosine-kinase inhibitors or hormonal agents should avoid breast feeding to avoid drug excretion in breast milk. Patients who will receive cytotoxic chemotherapy should be advised of the potential impact on their future fertility and offered fertility-preservation options. Breast cancer is the most common pregnancy-associated malignancy and is most frequently either invasive ductal or lobular carcinoma. Breast lymphoma is an exceedingly rare diagnosis that typically presents with unilateral disease in the seventh decade of life. Here, we present the case of a woman who presented with bilateral breast masses during the second trimester of pregnancy and was ultimately diagnosed with primary breast Burkitt's lymphoma.

Keywords: Breast cancer; Carcinogenesis; Chemotherapy; Oncology.

Publication types

  • Case Reports

MeSH terms

  • Breast Feeding
  • Breast Neoplasms* / pathology
  • Burkitt Lymphoma* / diagnosis
  • Burkitt Lymphoma* / drug therapy
  • Burkitt Lymphoma* / pathology
  • Female
  • Humans
  • Pregnancy