Chronic Kidney Disease Following Liver Transplant: Associated Outcomes and Predictors

Exp Clin Transplant. 2022 Feb;21(2):93-103. doi: 10.6002/ect.2022.0288. Epub 2023 Jan 16.

Abstract

Objectives: Liver transplant as a life-saving procedure in patients with end-stage liver disease may have some complications such as renal dysfunction. Improved postoperative management and immuno- suppressive therapy have increased long-term survival and thus increased late complications like chronic kidney disease. Our study aimed to investigate outcomes of chronic kidney disease in liver transplant recipients and the incidence, progression rates, and adjustable risk factors of chronic kidney disease after liver transplant.

Materials and methods: Related studies published in English were elicited from various international sources like the ISI Web of Science, PubMed/Medline, Google Scholar, and Scopus.

Results and conclusions: Chronic kidney disease as a long-term complication is common in liver transplant recipients whose survival is affected by renal function. Risk assessment of renal function before liver transplant and some nonrenal causes of chronic kidney disease after transplant could help reduce the risks associated with future renal outcomes.

Publication types

  • Review

MeSH terms

  • Humans
  • Kidney
  • Kidney Failure, Chronic* / etiology
  • Kidney Transplantation* / adverse effects
  • Liver Transplantation* / adverse effects
  • Renal Insufficiency, Chronic* / diagnosis
  • Renal Insufficiency, Chronic* / etiology
  • Renal Insufficiency, Chronic* / surgery
  • Risk Factors