Metastatic Adrenal PEComa: Case Report and Short Review of the Literature

Medicina (Kaunas). 2023 Jan 11;59(1):149. doi: 10.3390/medicina59010149.


PEComa has become a widely accepted entity, and increased recognition has led to descriptions of this tumor in a wide variety of anatomic sites, including the adrenal gland. PEComa (perivascular epithelioid cell tumor) is a mesenchymal tumor composed of perivascular cells, and the most frequent sites of PEComas are the uterus and retroperitoneum. The incidence is <1 per 1,000,000 people. We report a case of adrenal metastatic PEComa in a 63-year-old man discovered by a spontaneous hematoma of the rectus abdominis. In our case, PEComa of the adrenal gland was a significant diagnostic dilemma as the morphologic and immunophenotypic features of this neoplasm may easily be confused with those of other more commonly encountered lesions.

Keywords: PEComa; adrenal incidentaloma; metastatic PEComa.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Female
  • Humans
  • Male
  • Middle Aged
  • Perivascular Epithelioid Cell Neoplasms* / diagnosis

Grants and funding

This research received no external funding.