Cardiovascular and Cerebrovascular Response to RedBull® Energy Drink Intake in Young Adults

Anatol J Cardiol. 2023 Jan;27(1):19-25. doi: 10.14744/AnatolJCardiol.2022.2315.


Background: Energy drinks contain caffeine, taurine, sucrose, vitamins, and other amino acids. The dosage of these varies depending on the drink chosen. Several studies on energy drinks have been carried out, but the results obtained are still inconsistent as well as the risk associated with consumption. This study analyzed the cardio- and cerebrovascular responses after consumption of an energy drink - RedBull® - under standardized pre- and post-ingestion conditions and its impact on the cardiovascular and cerebrovascular system.

Methods: A sample of 30 healthy young adult females was recruited and subjected to 3 moments of evaluation: at baseline, 30 minutes after ingesting the energy drink, and 60 minutes after ingesting it according to a non-randomized pre-post intervention study design.

Results: It is found that over time there are significant changes in peak systolic velocity (P =.006) and endodiastolic velocity (P <.001) of common carotid artery, peak systolic velocity (P =.007), and endodiastolic velocity (P <.001) of internal carotid artery, peak systolic velocity (P =.004), end endodiastolic velocity (P =.013) of the external carotid artery, endodiastolic velocity (P =.042) of the middle cerebral artery, cardiac output (P =.004), and heart rate (P <.001).

Conclusions: After the consumption of Redbull®, there was a decrease in the velocities of the carotid arteries and the middle cerebral artery as well as a decrease in cardiac output accompanied by a decrease in heart rate and a slight, although not significant, increase in systolic and diastolic blood pressures. However, it is still unclear which pathophysiological mechanisms are responsible for these changes.

Publication types

  • Clinical Trial

MeSH terms

  • Blood Flow Velocity / physiology
  • Blood Pressure
  • Caffeine
  • Cardiovascular System*
  • Energy Drinks*
  • Female
  • Heart Rate
  • Humans
  • Young Adult


  • Caffeine