Identification of the γδ IEL-secreted Paneth Cell Protective Factor API5 as a Promising Therapeutic Target for ATG16L1-associated Crohn's Disease

Gastroenterology. 2023 Jun;164(7):1337-1338. doi: 10.1053/j.gastro.2023.01.015. Epub 2023 Jan 19.
No abstract available

Publication types

  • Comment

MeSH terms

  • Apoptosis Regulatory Proteins / metabolism
  • Autophagy
  • Autophagy-Related Proteins / genetics
  • Autophagy-Related Proteins / metabolism
  • Biological Transport
  • Crohn Disease* / diagnosis
  • Crohn Disease* / drug therapy
  • Crohn Disease* / metabolism
  • Humans
  • Nuclear Proteins / metabolism
  • Paneth Cells / metabolism
  • Protective Factors

Substances

  • Autophagy-Related Proteins
  • API5 protein, human
  • Nuclear Proteins
  • Apoptosis Regulatory Proteins
  • ATG16L1 protein, human