Sequential, Multiple Assignment, Randomized Trial Designs

Kelley M Kidwell; Daniel Almirall

doi:10.1001/jama.2022.24324

Sequential, Multiple Assignment, Randomized Trial Designs

JAMA. 2023 Jan 24;329(4):336-337. doi: 10.1001/jama.2022.24324.

Authors

Kelley M Kidwell¹, Daniel Almirall^{2

3}

Affiliations

¹ Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor.
² Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor.
³ Department of Statistics, University of Michigan, Ann Arbor.

No abstract available

Plain language summary

This JAMA Guide to Statistics and Methods explains sequential, multiple assignment, randomized trial (SMART) study designs, in which some or all participants are randomized at 2 or more decision points depending on the participant’s response to prior treatment.

Publication types

Randomized Controlled Trial
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Randomized Controlled Trials as Topic*
Research Design*

Plain language summary

Publication types

MeSH terms

Grants and funding