Evaluation of the effect of fish oil in the prevention of pressure ulcers in patients admitted to the intensive care unit

Contemp Clin Trials Commun. 2023 Jan 16:32:101063. doi: 10.1016/j.conctc.2023.101063. eCollection 2023 Apr.

Abstract

Introduction: Today, the anti-inflammatory property of fish oil is used to heal wounds, but this property has not been investigated to prevent the occurrence of pressure ulcers. So the research team decided to evaluate this feature as well.

Materials and methods: This clinical trial study was performed on 102 patients admitted to the intensive care unit located at Besat Hospital in 2020. Samples were assigned to three groups control, placebo, and intervention using permutation blocks. Before the intervention, the questionnaire of demographic and clinical variables, level of consciousness, Braden scale, and short nutritional status questionnaire was completed by the main researcher. In the intervention group, in addition to routine care, 2 cc of fish oil was gently rubbed into the sacrum once a day for 5 days. The same intervention was repeated in the placebo group, with the difference that soybean oil was used instead of fish oil, and the control group received only the usual care. The daily evaluation of pressure ulcers by one of the ICU nurses lasted up to 6 days.

Results: The results showed that there was a significant difference in the incidence of pressure ulcers in the three groups (P = 0.043). The risk of pressure ulcers in the control group was 11.9 and 2.7 times higher than the fish oil group and placebo group (P = 0.023) & (P = 0.132).

Conclusion: The use of topical fish oil can be effective in preventing pressure ulcers.

Keywords: Fish oil; Intensive care unit; Pressure ulcer; Soybean oil.