Maintenance and dynamic reprogramming of chromatin organization during development

Plant J. 2024 May;118(3):657-670. doi: 10.1111/tpj.16119. Epub 2023 Feb 17.


Controlled transcription of genes is critical for cell differentiation and development. Gene expression regulation therefore involves a multilayered control from nucleosome composition in histone variants and their post-translational modifications to higher-order folding of chromatin fibers and chromatin interactions in nuclear space. Recent technological advances have allowed gaining insight into these mechanisms, the interplay between local and higher-order chromatin organization, and the dynamic changes that occur during stress response and developmental transitions. In this review, we will discuss chromatin organization from the nucleosome to its three-dimensional structure in the nucleus, and consider how these different layers of organization are maintained during the cell cycle or rapidly reprogrammed during development.

Keywords: Arabidopsis; chromatin; histone modifications; histone variants; nuclear architecture.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Cycle / genetics
  • Cell Differentiation
  • Cell Nucleus / genetics
  • Cell Nucleus / metabolism
  • Chromatin Assembly and Disassembly
  • Chromatin* / genetics
  • Chromatin* / metabolism
  • Histones / genetics
  • Histones / metabolism
  • Nucleosomes* / genetics
  • Nucleosomes* / metabolism
  • Protein Processing, Post-Translational


  • Chromatin
  • Nucleosomes
  • Histones