Sudden anisocoria in a healing pediatric multitrauma patient

JAAPA. 2023 Feb 1;36(2):1-3. doi: 10.1097/01.JAA.0000902876.57194.e3.


This article describes a teenager who developed anisocoria with no obvious neurologic deficits or decline after a motor vehicle accident. The condition resolved over several hours before reappearing in the opposite eye 2 days later. Again no clinical neurologic deficits were noted and the condition resolved after several hours. The patient's asymptomatic anisocoria was finally determined to be secondary to aerosolized ipratropium treatments and an ill-fitting mask.

MeSH terms

  • Accidents, Traffic
  • Adolescent
  • Anisocoria* / diagnosis
  • Anisocoria* / etiology
  • Child
  • Humans
  • Ipratropium
  • Multiple Trauma*


  • Ipratropium