Risk Factors for Reinfection with SARS-CoV-2 Omicron Variant among Previously Infected Frontline Workers

Emerg Infect Dis. 2023 Mar;29(3):599-604. doi: 10.3201/eid2903.221314. Epub 2023 Jan 26.


In a cohort of essential workers in the United States previously infected with SARS-CoV-2, risk factors for reinfection included being unvaccinated, infrequent mask use, time since first infection, and being non-Hispanic Black. Protecting workers from reinfection requires a multipronged approach including up-to-date vaccination, mask use as recommended, and reduction in underlying health disparities.

Keywords: COVID-19; SARS-CoV-2; United States; coronaviruses; frontline workers; mRNA vaccines; omicron variant; reinfection; respiratory infection; risk factors; vaccine effectiveness; viruses; zoonoses.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • COVID-19*
  • Humans
  • Reinfection*
  • Risk Factors
  • SARS-CoV-2

Supplementary concepts

  • SARS-CoV-2 variants