Generalization of Young-Laplace, Kelvin, and Gibbs-Thomson equations for arbitrarily curved surfaces

Abstract

The Young-Laplace, Kelvin, and Gibbs-Thomson equations form a cornerstone of colloidal and surface sciences and have found successful applications in many subfields of physics, chemistry, and biology. The Gibbs-Thomson effect, for example, predicts that small crystals are in equilibrium with their liquid melt at a lower temperature than large crystals and the positive interfacial energy increases the energy required to form small particles with a high curvature interface. In cases of liquids contained within porous media (confined geometry), the effect indicates decreasing the freezing/melting temperatures and the increment of the temperature is inversely proportional to the pore size. These phenomena can be reformulated for Gaussian maps of macromolecules and can be asked the following question: can one use the equations for predicting the melting temperature and shape of polymer chains in confined geometries? The answer is no, mainly because macromolecules form highly curved surfaces (Gaussian maps), and the equations hold only for simple geometries (sphere, plane, or cylinder). Here, we present general Young-Laplace, Kelvin, and Gibbs-Thomson equations for arbitrarily curved surfaces and apply them to predict temperature distribution on a few protein surfaces. Also, after increased interest toward liquid/liquid phase separation in biology, we derive generic Ostwald ripening and show that for shape-changing condensates, instead of a monotonic growing mechanism, a variety of processes are possible. Due to the generality of equations, we clarify that at appropriate internal/external pressure conditions systems, bounded by surfaces, may adopt any shape and thermal stability is strongly influenced by the geometries of confined spaces.