A rare case of pancytopenia causing- Sheehan's syndrome: Case report and literature review

Clin Case Rep. 2023 Jan 23;11(1):e6827. doi: 10.1002/ccr3.6827. eCollection 2023 Jan.


We describe the case of a 58-year-old woman who was presented with pancytopenia and hypofibrinogenemia. Treatment with iron supplementation was not satisfactory. Physical findings and a history of a massive postpartum hemorrhage suggested Sheehan's syndrome(SS). After thyroxine and glucocorticoid replacement therapy, the blood cell count improved. SS is a rare etiology of hemocytopenia, of which hematologists need to be aware. We conclude that hormonal therapy can produce full hematological recovery.

Keywords: Sheehan's syndrome; glucocorticoid; gum bleeding; pancytopenia; thyroxine.

Publication types

  • Case Reports