Case of apparent mpox reinfection

Sex Transm Infect. 2023 Jun;99(4):283-284. doi: 10.1136/sextrans-2022-055736. Epub 2023 Jan 27.


We present an apparent second episode of mpox (monkeypox) genital ulcerative disease in a non-immunosuppressed MSM (man who has sex with men) patient who had completely recovered from a primary mpox infection 4 months previously. The patient had also received a complete two-dose course of smallpox vaccination between the two presentations. This case highlights the importance of continuing to include mpox in the differential diagnoses for individuals presenting with genital or mucosal ulceration, regardless of assumed immunity derived from prior infection or vaccination.

Keywords: Disease Transmission, Infectious; SEXUAL HEALTH; VACCINATION; VIROLOGY.

MeSH terms

  • Diagnosis, Differential
  • Homosexuality, Male
  • Humans
  • Male
  • Monkeypox*
  • Reinfection
  • Sexual and Gender Minorities*
  • Urogenital Diseases*