Impact of HCV Treatment on Recurrence of Hepatocarcinoma After Liver Transplantation

Transplant Proc. 2023 Jan-Feb;55(1):197-198. doi: 10.1016/j.transproceed.2022.12.011. Epub 2023 Jan 25.


The treatment of hepatitis C virus (HCV) has been a revolution in hepatology. Since the beginning of transplantation, liver cirrhosis and hepatocarcinoma on HCV cirrhosis has been the main etiology of liver transplantation. We set out to analyze the impact that C virus treatment has had on liver transplantation. To do so, we divided our cohort into 2 periods, one before virus treatment (from 2000-2014) and one after the onset of treatment (2014-2020). Taking into account this differentiation, we analyzed the percentage of patients transplanted for hepatocarcinoma over cirrhotic liver by HCV in both groups. Among the patients transplanted for HCV, we analyzed whether there were differences in hepatocarcinoma recurrences according to their serologic status at the time of transplantation.

MeSH terms

  • Carcinoma, Hepatocellular* / complications
  • Hepacivirus
  • Hepatitis C* / etiology
  • Humans
  • Liver Cirrhosis / complications
  • Liver Neoplasms* / complications
  • Liver Transplantation* / adverse effects
  • Neoplasm Recurrence, Local
  • Recurrence