Robot-assisted TAMIS: a systematic review of feasibility and outcomes

Surg Endosc. 2023 May;37(5):3398-3409. doi: 10.1007/s00464-022-09853-z. Epub 2023 Jan 27.


Background: In the advancement of transanal local excision, robot-assisted transanal minimal invasive surgery is the newest development. In the confined area of the rectum, robot-assisted surgery should, theoretically, be superior due to articulated utensils, video enhancement, and tremor reduction, however, this has not yet been investigated. The aim of this study was to review the evidence reported to-date on experience of using robot-assisted transanal minimal invasive surgery for treatment of rectal neoplasms.

Methods: A comprehensive literature search of Embase and PubMed from May to August 2021were performed. Studies including patients diagnosed with rectal neoplasia or benign polyps who underwent robot-assisted transanal minimal invasive surgery were included. All studies were assessed for risk of bias through assessment tools. Main outcome measures were feasibility, excision quality, and complications.

Results: Twenty-five studies with a total of 322 local excisions were included. The studies included were all retrospective, primarily case-reports, -series, and cohort studies. The median distance from the anal verge ranged from 3.5 to 10 cm and the median size was between 2.5 and 5.3 cm. Overall, 4.6% of the resections had a positive resection margin. The overall complication rate was at 9.5% with severe complications (Clavien-Dindo score III) at 0.9%.

Conclusion: Based on limited, retrospective data, with a high risk of bias, robot-assisted transanal minimal invasive surgery seems feasible and safe for local excisions in the rectum.

Keywords: NOTES transanal; RTS; Robot-assisted transanal minimal invasive surgery; Robotic TAMIS; Robotic transanal surgery.

Publication types

  • Systematic Review
  • Review

MeSH terms

  • Anal Canal / surgery
  • Feasibility Studies
  • Humans
  • Margins of Excision
  • Rectal Neoplasms* / surgery
  • Rectum / surgery
  • Retrospective Studies
  • Robotics*
  • Transanal Endoscopic Surgery*
  • Treatment Outcome