Diagnosis of Rare Bone Infection Caused by Nocardia by 16S rRNA Gene Sequencing

Infect Drug Resist. 2023 Jan 20:16:347-353. doi: 10.2147/IDR.S392342. eCollection 2023.


Nocardia is an aerobic actinomycete that causes serious opportunistic infections in immunocompromised individuals. Gene sequencing is the gold standard for pathogenic bacteria diagnosis. This study uses 16S rRNA gene sequencing to diagnose three cases of bone infections caused by Nocardia, including one rare case (N. cyriacigeorgica), and the clinial features, etiological characteristics, treatment, and prognosis of the patients.

Keywords: 16S rRNA gene sequencing; Nocardia; bone infection; clinical features.

Publication types

  • Case Reports

Grants and funding

The authors received no financial support for the research.