Physical activity in Norwegian teenagers and young adults with haemophilia A compared to general population peers

Haemophilia. 2023 Mar;29(2):658-667. doi: 10.1111/hae.14752. Epub 2023 Feb 1.


Introduction: Limited evidence exists on objectively measured habitual physical activity (PA) of young people with haemophilia (PWH).

Aims: To compare different outcomes of objective PA between young PWH A and controls using a commercial activity tracker.

Methods: We enrolled males aged 13-30 years with moderate and severe haemophilia A, without inhibitors on regular prophylaxis. PA was measured with the activity tracker Fitbit Charge 3 for 12 weeks. Control group data was obtained from ≈60,000 Fitbit users, matched on age, sex and measurement period. PA variables [steps, intensities, volume, activity types, exercise frequencies and proportion meeting the World Health Organization's moderate-to-vigorous PA (MVPA) recommendations] were compared between groups descriptively and using Welch's two-sample t-test and two-sample test of proportions.

Results: Forty PWH A were enrolled (mean age 19.5 years, 50% teenagers, 50% adults, three (7.5%) with moderate and 37 (92.5%) with severe haemophilia). Mean daily steps and minutes MVPA were similar between PWH and controls. PWH spent more time in light PA (mean 227 vs. 192 min/day, P = .033) and exercised more frequently (mean 5.6 vs. 3.9 exercise sessions/week, P < .001). Among teenagers, 40% PWH and 8% controls reached MVPA recommendations, compared to 95% and 100% among adults. The most common type of PA was walking.

Conclusion: This cohort of young PWH A on prophylactic treatment had PA levels comparable to controls. Still, a considerable proportion of teenagers did not meet the recommended weekly volume of MVPA, and we encourage clinicians to have a particular focus on promoting PA for this group.

Keywords: Fitbit; exercise; haemophilia; haemophilia A; physical activity.

MeSH terms

  • Adolescent
  • Adult
  • Exercise
  • Fitness Trackers
  • Hemophilia A* / epidemiology
  • Humans
  • Male
  • Walking
  • Young Adult

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