Evaluation of non-research payments from pharmaceutical companies to urologists in Japan between 2016 and 2019

Int Urogynecol J. 2023 Jun;34(6):1285-1292. doi: 10.1007/s00192-023-05463-y. Epub 2023 Feb 1.

Abstract

Objective: To evaluate the magnitude and trends in personal payments from pharmaceutical companies to urologists in Japan.

Methods: This cross-sectional study examined the personal payments made to urologists by the major pharmaceutical companies in Japan between 2016 and 2019. Descriptive analyses were performed on the payment data. All urologists board-certified by the Japanese Urological Association as of March 2022 were included in this study. Trends in personal payments were assessed using the population-averaged generalized estimating equations with panel data of per-physician personal payments.

Results: Among 7016 active board-certified urologists, 4962 (70.7%) accepted 53,070 payments totaling $36,424,239 for reimbursement of lecturing, writing, and consulting compensations from 66 pharmaceutical companies between 2016 and 2019. The median payments per urologist receiving payments were $1714 [interquartile range(IQR): $700-$4583] in payment amounts and 4.0 (IQR: 2.0-10.0) in the number of payments. Only 1%, 5%, 10%, and 25% of top-paid urologists accepted 36.2%, 64.8%, 75.8%, and 90.1% of overall payments respectively. The payments per urologist and the number of payment contracts had annually increased over this period by 4.1% (95% CI: 2.3%-6.0%, p < 0.001) and 2.4% (95% CI: 1.2%-3.7%, p < 0.001), but there was no significant change in the number of urologists receiving payments, with a relative average annual change of 0.7% (95% CI: -0.15%-1.6%, p = 0.10) between 2016 and 2019.

Conclusion: Most urologists received personal payments for lecturing, consulting, and writing compensations from pharmaceutical companies in Japan. The payments from pharmaceutical companies had been increasing over the 4-year period. These payments were substantially concentrated on a small number of urologists.

Keywords: Ethics; Financial conflicts of interest; Japanese Urological Association; Pharmaceutical payments; Urologists.

MeSH terms

  • Conflict of Interest
  • Cross-Sectional Studies
  • Disclosure
  • Drug Industry*
  • Humans
  • Japan
  • Pharmaceutical Preparations
  • United States
  • Urologists*

Substances

  • Pharmaceutical Preparations