[A case of caseous calcification of mitral annulus resulting in multiple cerebral infarctions]

Rinsho Shinkeigaku. 2023 Feb 25;63(2):97-100. doi: 10.5692/clinicalneurol.cn-001816. Epub 2023 Jan 31.
[Article in Japanese]

Abstract

The patient is a 73-year-old woman. She presented with dysarthria, and a head MRI revealed multiple acute cerebral infarctions in the bilateral cerebral hemisphere and cerebellar hemisphere. Transesophageal echocardiography after admission revealed a 16 mm large mobile calcification of the mitral annulus (caseous calcification of the mitral annulus; CCMA) on the posterior apex of the mitral valve annulus. Since the CCMA had a high risk of relapse, and a new infarction was detected on the 8th day, resection of the mass and mitral valve replacement surgery were performed. CCMA is a subtype of mitral annular calcification (MAC). When calcification progresses from the MAC state to form a mass, it is called a calcified amorphous tumor; CAT. Reports of embolic cerebral infarction caused by CAT are rare, but this is a rare report of an embolic cerebral infarction from CCMA presenting as CAT.

Keywords: calcified amorphous tumor; caseous calcification of the mitral annulus; mitral annular calcification; multiple cerebral infarctions.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Calcinosis* / pathology
  • Cerebral Infarction / pathology
  • Echocardiography, Transesophageal
  • Female
  • Heart Valve Diseases*
  • Humans
  • Mitral Valve / pathology