18 F-Choline Versus 68 Ga-PSMA-11 PET/CT Imaging Comparison in Incidental Clear Cell Renal Cell Carcinoma

Luca Urso; Giovanni Christian Rocca; Licia Uccelli; Carmelo Ippolito; Mirco Bartolomei

doi:10.1097/RLU.0000000000004515

18 F-Choline Versus 68 Ga-PSMA-11 PET/CT Imaging Comparison in Incidental Clear Cell Renal Cell Carcinoma

Clin Nucl Med. 2023 Apr 1;48(4):e178-e180. doi: 10.1097/RLU.0000000000004515. Epub 2023 Feb 1.

Authors

Luca Urso, Giovanni Christian Rocca¹, Licia Uccelli², Carmelo Ippolito¹, Mirco Bartolomei³

Affiliations

¹ Urology Unit, Surgical Department, University Hospital of Ferrara, Ferrara, Italy.
² From the Translational Medicine Department, Ferrara University, Ferrara, Italy.
³ Nuclear Medicine Unit, Oncological Medical and Specialists Department, University Hospital of Ferrara, Ferrara, Italy.

PMID: 36728284
DOI: 10.1097/RLU.0000000000004515

Abstract

Few articles in literature describe the potential usefulness of 18 F-choline PET/CT and particularly 68 Ga-PSMA-11 PET/CT in imaging of clear cell renal cell carcinoma (ccRCC). We report a unique comparison in literature between the 2 radiotracers in a patient who underwent left nephrectomy with diagnosis of ccRCC, grade 3. 68 Ga-PSMA-11 PET/CT confirmed its emerging role in imaging ccRCC, as the incidentally detected renal neoplasm showed a significant higher uptake in comparison to 18 F-choline PET/CT, inducing surgical indication.

MeSH terms

Carcinoma, Renal Cell*
Choline
Gallium Radioisotopes
Humans
Kidney Neoplasms*
Positron Emission Tomography Computed Tomography / methods
Radiopharmaceuticals

Substances

Choline
Radiopharmaceuticals
Gallium-68
Gallium Radioisotopes