Application of ablative therapy for intrahepatic recurrent hepatocellular carcinoma following hepatectomy

World J Gastrointest Surg. 2023 Jan 27;15(1):9-18. doi: 10.4240/wjgs.v15.i1.9.

Abstract

The post-hepatectomy recurrence rate of hepatocellular carcinoma (HCC) is persistently high, affecting the prognosis of patients. An effective therapeutic option is crucial for achieving long-term survival in patients with postoperative recurrences. Local ablative therapy has been established as a treatment option for resectable and unresectable HCCs, and it is also a feasible approach for recurrent HCC (RHCC) due to less trauma, shorter operation times, fewer complications, and faster recovery. This review focused on ablation techniques, description of potential candidates, and therapeutic and prognostic implications of ablation for guiding its application in treating intrahepatic RHCC.

Keywords: Ablation techniques; Combined therapy; Hepatocellular carcinoma; Radiofrequency ablation; Recurrence; Therapeutic index.

Publication types

  • Review