Vitamin A: a key coordinator of host-microbe interactions in the intestine

BMB Rep. 2023 Mar;56(2):133-139. doi: 10.5483/BMBRep.2023-0005.

Abstract

The human intestine is home to a dense community of microbiota that plays a key role in human health and disease. Nutrients are essential regulators of both host and microbial physiology and function as key coordinators of host-microbe interactions. Therefore, understanding the specific roles and underlying mechanisms of each nutrient in regulating the host-microbe interactions will be essential in developing new strategies for improving human health through microbiota and nutrient intervention. This review will give a basic overview of the role of vitamin A, an essential micronutrient, on human health, and highlight recent findings on the mechanisms by which it regulates the host-microbe interactions. [BMB Reports 2023; 56(3): 133-139].

Publication types

  • Review
  • News

MeSH terms

  • Host Microbial Interactions*
  • Humans
  • Intestines
  • Microbiota* / physiology
  • Vitamin A

Substances

  • Vitamin A

Grants and funding

ACKNOWLEDGEMENTS This study was supported by Bumsuk Academic Research Fund in 2022.