GDF15 analogs as obesity therapeutics

Cell Metab. 2023 Feb 7;35(2):227-228. doi: 10.1016/j.cmet.2023.01.002.


There is increasing interest in GDF15 analogs as therapeutic agents for obesity. In this issue of Cell Metabolism, Benichou et al. report the first clinical trial of such a drug in obese humans.

Publication types

  • Comment

MeSH terms

  • Growth Differentiation Factor 15*
  • Humans
  • Obesity* / drug therapy
  • Obesity* / metabolism


  • GDF15 protein, human
  • Growth Differentiation Factor 15