Possible spread of SARS-CoV-2 in domestic and wild animals and body temperature role

Virus Res. 2023 Apr 2;327:199066. doi: 10.1016/j.virusres.2023.199066. Epub 2023 Feb 10.


The COVID-19 pandemic was officially announced in March 2020 and is still moving around the world. Virus strains, their pathogenicity and infectivity are changing, but the ability is fast to spread and harm people's health remained, despite the seasonality seasons and other circumstances. Most likely, humanity is doomed for a long time to coexistence with this emergent pathogen, since it is already circulating not only among the human population, but and among fauna, especially among wild animals in different regions of the planet. Thus, the range the virus has expanded, the material and conditions for its evolution are more than enough. The detection of SARS-CoV-2 in known infected fauna species is analyzed and possible spread and ongoing circulation of the virus in domestic and wild animals are discussed. One of the main focus of the article is the role of animal body temperature, its fluctuations and the presence of entry receptors in the susceptibility of different animal species to SARS-CoV-2 infection and virus spreading in possible new ecological niches. The possibility of long-term circulation of the pathogen among susceptible organisms is discussed.

Keywords: Animals; Body temperature role; Regional spreading; Reservoirs; SARS-CoV-2.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Animals, Wild
  • Body Temperature
  • COVID-19*
  • Humans
  • Pandemics
  • SARS-CoV-2*