[Toxic components of the venom of the cellar spider Segestria florentina]

Bioorg Khim. 1987 Aug;13(8):1013-8.
[Article in Russian]

Abstract

Two neurotoxins and one insectotoxin have been isolated from venom of the cellar spider Segestria florentina, their homogeneity being proved by disk electrophoresis, isoelectric focusing, and analysis of N-terminal amino acid residues. The neurotoxins are polypeptides with molecular mass about 5000 D. For the insectotoxin, containing 35 amino acid residues with molecular mass 3988 D, the total primary structure is established.

Publication types

  • English Abstract

MeSH terms

  • Action Potentials / drug effects
  • Amino Acid Sequence
  • Amino Acids
  • Animals
  • Anura
  • Arthropod Venoms / analysis*
  • Chromatography, Gel
  • Chymotrypsin
  • Hydrolysis
  • In Vitro Techniques
  • Neuromuscular Junction / drug effects
  • Neuromuscular Junction / physiology
  • Neurotoxins / analysis*
  • Neurotoxins / pharmacology
  • Spider Venoms / analysis*
  • Spider Venoms / pharmacology

Substances

  • Amino Acids
  • Arthropod Venoms
  • Neurotoxins
  • Spider Venoms
  • Chymotrypsin