Can Multisystem Inflammatory Syndrome in Children Be Managed in the Outpatient Setting? An EHR-Based Cohort Study From the RECOVER Program

J Pediatric Infect Dis Soc. 2023 Apr 18;12(3):159-162. doi: 10.1093/jpids/piac133.


Using electronic health record data combined with primary chart review, we identified seven children across nine participant pediatric medical centers with a diagnosis of Multisystem Inflammatory Syndrome in Children (MIS-C) managed exclusively as outpatients. These findings should raise awareness of mild presentations of MIS-C and the option of outpatient management.

Keywords: COVID; inflammatory; multisystem; outpatients; syndromes.

MeSH terms

  • COVID-19*
  • Child
  • Cohort Studies
  • Humans
  • Outpatients*
  • Systemic Inflammatory Response Syndrome / diagnosis
  • Systemic Inflammatory Response Syndrome / therapy

Supplementary concepts

  • pediatric multisystem inflammatory disease, COVID-19 related