Effect of Patient and Family Centered I-PASS on adverse event rates in hospitalized children with complex chronic conditions

J Hosp Med. 2023 Apr;18(4):316-320. doi: 10.1002/jhm.13065. Epub 2023 Feb 14.


Background: Children with complex chronic conditions (CCCs) are at risk for adverse events (AEs) during hospitalizations.

Objective: We compared the effect of Patient and Family Centered (PFC)I-PASS on AE rates in children with and without CCCs.

Designs, settings, and participants: Patients were drawn from the PFCI-PASS study, which included 3106 hospitalized children from seven North American pediatric hospitals between December 2014 and January 2017.

Main outcome and measures: An effect modification analysis did not show difference in the intervention on children with and without CCCs (RRR 0.81, 95% CI [0.59-1.10]; p = .2).

Results: In multivariable analysis, the adjusted incidence rate ratiofor AEs in children with CCCs was 0.5 (95% CI = 0.3-0.9, p = .01) with PFC I-PASS exposure; there was no statistically significant change in AEs for children without CCCs [IRR 0.6 (95% CI = 0.3-1.2; p = .1)].

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child
  • Child, Hospitalized*
  • Chronic Disease
  • Hospitalization*
  • Humans
  • Racial Groups