Microphthalmia, aphakia and agenesis of the optic chiasm and tract in a wild fox squirrel (Sciurusniger)

J Comp Pathol. 2023 Feb:201:109-113. doi: 10.1016/j.jcpa.2023.01.001. Epub 2023 Feb 13.

Abstract

We describe gross and histopathological features of multiple ocular and neuro-ophthalmic abnormalities in a fox squirrel (Sciurus niger). Ophthalmic findings included severe bilateral microphthalmos, with the right eye more affected than the left. Histopathology confirmed severe microphthalmia, aphakia, disorganized retinal tissue and small optic nerves, as well as agenesis of the optic chiasm and optic tract. This combination of neuro-ophthalmic abnormalities has not been previously described in wild animals.

Keywords: aphakia; fox squirrel; microphthalmos; optic chiasm; optic tract; wildlife.

MeSH terms

  • Animals
  • Aphakia* / pathology
  • Aphakia* / veterinary
  • Microphthalmos* / pathology
  • Microphthalmos* / veterinary
  • Optic Chiasm / pathology
  • Retina / pathology
  • Rodent Diseases* / pathology
  • Sciuridae